Abstract: Objective To investigate the application chlorhexidine gargle and oral care in gingivitis patients.Methods 100 gingivitis patients were randomly divided into observation group (50 cases)and control group (50 cases).The control group were treated with conventional treat-ment.On the basis of the observation group,chlorhexidine gargle and oral nursing intervention were added in the observation group.The plaque index (PLI)and gingival index (GI)of patients 2 weeks and 4 weeks after treatment were observed.Results The PLI and GI of 2 groups patients had no significant difference before treatment (P >0.05).After 2 weeks treatment,the observa-tion group were significantly improved (P <0.01),also the control group (P <0.01);After 4 weeks treatment,the observation group improved more significantly (P <0.05),the control group PLI compared with those before treatment were significantly improved (P <0.01),GI improved more significantly.Comparison between groups,the observation group PLI and GI were significant-ly lower than those in the control group (P <0.01).Conclusion gingivitis patients using the adju-vant therapy chlorhexidine gargle fluid and oral nursing intervention can significantly improve the PLI and the GI,worth clinical promotion.