Abstract: Objective To study the effect of comprehensive nursing on deep venous throm-bosis after operation in hip fracture patients.Methods 105 patients with hip fracture surgery were divided into observation group (53 patients)and control group (52 patients).The control group was given routine nursing while the observation group was given comprehensive nursing.Aware of knowledge about diseases,compliance rate of health behavior,incidence of postoperative deep vein thrombosis (DVT),the incidence rate of lower limb pain and swelling and hospitalization time were compared.Results Knowledge about the disease,treatment compliance rate,persistence rate of functional exercise in the observation group were significantly higher than that of control group (P <0.01).Postoperative DVT,lower limb pain and swelling and hospitalization time were significantly lower than that in the control group (P <0.05 or P <0.01).Conclusion Compre-hensive nursing intervention can effectively improve disease awareness of patients and health behav-ior compliance rate,reduce the incidence rate of postoperative DVT formation as well as lower limb pain and swelling,promote the rehabilitation process and shorten the hospitalization time.