36例胰腺神经内分泌肿瘤的影像学及病理学比较

Comparative study of radiological and pathological findings of neuroendocrine tumors in pancreas

  • 摘要: 目的:比较分析胰腺神经内分泌肿瘤(NET)的影像学及其病理学特征。方法对本院2009-2012年收治的36例具有完整影像学资料和病理结果的胰腺 NET 患者的临床特征进行比较分析。结果①不同病理级别肿瘤的瘤灶位置、边界清晰与否、是否伴囊变坏死和(或)钙化间差异均无统计学意义。不同级别肿瘤强化程度各参数均表现出随病理级别增高而下降趋势,其中 A1、A2参数差异明显(P <0.05),具有统计学意义;②良、恶性肿瘤及功能,无功能肿瘤最大径之间差异有统计学意义(P <0.05),而神经内分泌标志物反应并无明显差异(P >0.05),不具有统计学意义。结论通过 CT 动态增强扫描有助于胰腺 NET 术前分级,其肿瘤级别越高,强化越差,而肿瘤的最大直径对判断肿瘤为良性或恶性具有指导性作用。

     

    Abstract: Objective To comparatively analyze the radiological and pathological findings of neuroendocrine tumor in pancreas.Methods The clinical features of 36 patients with complete ra-diologic and pathologic diagnosis of neuroendocrine tumor of pancreas treated in our hospital from 2009 to 2012 were analyzed.Results The difference was not significantly different in tumor loca-tion,distinct outline,necrosis and calcification.The higher the tumor enhancement was,the more declining of the pathology grade .The difference was significant in A 1 and A 2 parameters (P <0.05).The difference was significant in benign and malignant tumor and the maximum diameter of unfunctional tumor.However,the difference was not significant in refection of remarker of en-docrine(P >0.05).Conclusion The dynamic enhancing scanning is helpful to grade the neuroen-docrine tumors in pancreas before operation.The more grading the tumor is,the worse the enhance-ment is.And the maximum diameter of the tumor is indicative to diagnose benign tumor or malig-nant tumor.

     

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