Abstract: Objective To study the clinical significance of ST-T changes in electrocardio-gram to diagnose coronary heart disease in hypertensive patients.Methods One hundred and twelve patients with hypertension accompanied by chest pain in our hospital were divided into ST-T group with dynamic changes with 46 patients and ST-T group without dynamic changes with 66 patients according to ST-T changes.All patients were given electrocardiogram monitoring and coronary an-giography,and the relationship between the results of coronary angiography and ST-T dynamic changes was analyzed in both groups.Results There were 36 patients (32.1%)of positive coro-nary artery and 10 patients (8.9%)of negative coronary artery in ST-T group with dynamic changes,whereas there were 18 patients (16.1%)of positive coronary artery and 48 patients (42. 9%)of negative coronary artery in ST-T group without dynamic changes.The positive rate of coro-nary artery was evidently higher in ST-T group with dynamic changes than that in ST-T group without dynamic changes,and the difference was statistical significant.Conclusion ST-T dynamic changes in electrocardiogram of hypertensive patients has a certain correlation with the diagnosis of coronary heart disease,which can be considered as one of the references to diagnose the coronary heart disease.