Abstract: Obj ective To observe the influence of carotid artery stenting (CAS)on the life quality and cognitive function of patients with severe carotid artery stenosis.Methods 64 carotid artery stenosis patients treated with CAS were collected. Mini -mental state examination (MMSE),activity of daily living scale (ADL),rapid verbal retrieve (RVR),digit span (DS),vi-sual retention test (VRT)and WHOQOL were applied for patients to assess efficacy at the time points of before operation and 3 ,12 months after operation.Results The success rate of CAS was 100%,and no complications such as embolism and internal carotid artery thrombosis were ob-served .The rate of carotid artery stenosis decreased after operation,while the carotid blood flow improved significantly.3 and 12 months after treatment,MMSE,VR and DS scores increased sig-nificantly,and ADL score decreased significantly,and the increased and decreased ranges at the time of 12 months after treatment were significantly larger than those at the time of 3 months after treatment.3 months after treatment,VRT right score and WHOQOL score increased,while VRT wrong score reduced significantly.Conclusion CAS can significantly improve the life quality and cognitive function of patients with carotid artery stenosis,so it is worthy of clinical application and popularization.