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摘要: 原发性醛固酮增多症(PA)是由于肾上腺皮质肿瘤或增生导致醛固酮分泌增多,引起水钠潴留,抑制肾素-血管紧张素系统,是继发性高血压的常见病因.本文对45例PA患者采用24 h动态血压监测(ABPM),分析24 h平均血压、脉压、血压负荷及昼夜节律等多项指标,并与原发性高血压患者进行比较,探讨PA患者的动态血压特征.
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中国高血压防治指南修订委员会. 中国高血压防治指南2010 [J]. {H}中华心血管病杂志, 2011(7):579.doi: 10.3760/cma.j.issn.0253-3758.2011.07.002. Fagugli R M, Taglioni C. Changes in the perceived epidemiology of primary hyperaldosteronism [J]. Int J Hypertens, 2011.1. VKerr C, King R, Bumett S. Which adult patients with hypertension should be screened for primary hyperaldosteronism [J]. J Okla State Med Assoc, 2011, (11/12):406. Matsukawa T, Miyamoto T. Does infusion of ANG Ⅱ increase muscle sympathetic nerve activity in patients with primary aldosteronism [J]. {H}American Journal of Physiology Regulatory Integrative and Comparative Physiology, 2008(6):R1873. Baba Y, Hayashi S, Nakajo M. Are catecholamine-derived indexes in adrenal venous sampling useful for judging selectivity and laterality in patients with primary aldcsteronism [J]. {H}ENDOCRINE, 2012. di Murro A, Petramala L, Cotesta D. Renin-angiotensin-aldosterone system in patients with sleep apnoea:prevalence of primary aldosteronism [J]. J Renin Angiotensin Aldosterone Syst, 2010(3):165. Kontak A C, Wang Z, Arbique D. Reversible sympathetic overactivity in hypertensive patients with primary aldosteronism [J]. {H}Journal of Clinical Endocrinology and Metabolism, 2010, (10):4756. de la Sierra A, Segura J, Gorostidi M. Diurnal blood pressure variation, risk categories and antihypertensive treatment [J]. {H}Hypertension Research, 2010(8):767. -
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